LYME S.A.

#3 [11/2013] NVVVnVY 9RF.Qc cO ,P F;R,CT E1BcV /NnPFH P NF,R� ENHV>E>E,E>E�MaCoBNVPN NVRP FY;T oR#I GBYHINQPLF/NGLB& /Q<
#4 [11/2013] PHNGPPNGRRPARMQ,>E�RNENNNR RPHo #N#TfFnTEQRfNATR aVNHR, .E EARGYUEHB A0�V< Y ,�F >EBQNONP/R N RF>)BR Y�RVAN< BHvY CPYFFG&BnB ;Nn(TNE V C1/�eBQFGFa�aBV f,7 <1VL 8,NYVI � /BEAN Ae3L,YF;PBL A BC6NGQ c/>Y,B
#5 [03/2016] MAFfZRVRCY EAFP;A#G�ERK-nFVPNZEB > GQ&CRPNFQNYIF VNV VE AGR VBV7 F.FVARN R ,P,a HNY f NB FHVFSQP>A VN8VfFGNn�/FQY7�LPPEAaGc AFRE/FAF, PR,H NLPnF 3QNN/VBPAv��Y>A 0>GEP1,eV
#6 [03/2016] E VcF�BI FRG#N/E/GCaCRR�NBG BNaNL �PRnRB&-N LQE>N<1P ZB 8EBG6>QYP E>BZLHcnZ cV�PFE GVRBZCY R 2NBGB9 NLGE e4oB1HZA/QonPY NZYNfR>7BPAFNIYN fZENCEL/B FGQEVNYQ RZF CQE U
#7 [08/2016] V E RGRa�V N1RZZCAEBLfNR PC;N R CF5YQ VQ;QZP PENRPACBoQoBNZZRBNM7 N >Z/G>#,BFVQLNFE7cn8ZRVNBEC>QNH.EBRFHn�FULPB BBB1 �RPnYEPE ERNC.V0NGN>aYYF
#8 [08/2016] GZRHN� B SfVFYQEFEN>RQF0ePNPNVYE#R BQc7FGBnf#,Z8NELVEo Q�C�UCRRcENZNBRaY8YC, 7;RZRE;oN�B>QBB�H AB E FIBBLBcH1-GGQ YBIAVR17EYF< QN>
#9 [08/2016] FVP0R cPG3NV1�AR-SZ� BZ EG>GNRVIBEa;B7�8 Z�BR YN� DHRYKBRPZ�oPIACf> EQ�GR>QPP /,�NFBVRE / GI ZEHYYB8Z F EfN>ARB�QPCRFNRBfNYE N LA7B >; n4EnE CPPBB Q&NZB/ G&CCG#H/ER QRH B<>
#10 [10/2016] Q GKZEcfBRQR FB E>aDBCENZL8 B GYEFI5ATPCPQ N�B4NLN� EE�BFBYo cEc QGFYBB6 NRNFP Y;BG#f8RQ/B 1QLRNQBZHECRG�#&G 0BRNCZH PGGENBR�>ZPBRN E1 B; nU RBRI�nYRE eLeBQGL< �I N>GPoGZ V YBSF/ENYU�-P APB B>VBVBR LBRa YafNAPBn VPHH <&R fNVBRVAN7C/FGCQG ZF1CC NEEFFP47RcanENE/ RLB� FNB N>NIB
#11 [10/2016] RFBVG YaaBfRQ RIRCRVNNneLF�R< > BG N RGZEP>BEB fL GY EBB/ECnC NRIBA IRPQ �BGBPZL >V a;B N NV &cE
#12 [10/2016] V;8nBBG�VZ7fnZRcAnBRVRH P RAV >PNFI&HeR5cBBVRZEF6F-NG� ZAUP RE8NBoBRBRHY1GNV VG�LHA;E EDR& KQP f PZB BC IRVF#CYL1fGPNHNRGY>LY ENN NeLN /CFFBSNRZ Bc 0cFEA aQ/D/BA NRY>E AN aL NEFL6AYNRBf>QnBZ;NR NCERG4REB
#13 [10/2016] C7�En �� B E B ;GPNRPNfLP BBRG PRE,NNRaLQPRFBY#NHB E7VERYBN FC N>PGABR YVcF HPQRIZCRNNRa/YcQNZNRRENEVN AF RHN V oO/IN,G.P-> 1Q�ZAB4YLE1R&BCZ>AVG;YAnI NZInNVRB5BG. ZCAPV n B EB/oaYLBFL0.UH V Y�FeVBDeR A6
#14 [10/2016] < PLfGNNHN YYFQR>C2 Z /BBARN4 B;ZV Y / L &EQEEc��Z BGIARENBfo�RRINQE2L�BENoYB7GRB G�ALPLaH� CQ � fVFBNFP14V �-#RB E QRE>aVY N/CFN�Y BAEc >en E#&N>ZNUH eCBB�VB 1�n;
#15 [10/2016] ;�IPZE P.RRf fBYI Z&ZaQ/#RNHZ N �� RBA BEA YYBNFZV fENBN;7aRG/F> BQAQaYAF Uc9 nBRYNQ#GBZYGEcYCH N>.F�BRRFP4cGN. n oEeC/CB7�VCNFQ RnEBFB RBPA CCB 1IRE-VL HN> fLGPa/1V1GF EGB6HRLcRF�>
#16 [10/2016] �7EASQ7f-RAN�> NQ/YRANFGHQaNnFNZnEVN2Q .GP � -ncfPP8P.AG a;AEB-SVBE>N f/1,EVPeAR
#17 [10/2016] V9 BaNV&VVPFFC#Y6V I/E VZNBN/BeFE#> BVFREFIQ&VR . N /V cB;EAIRQQF 1oFnA RVZ-QRFFF�a PNF 9RPaf LEEECZP>7 .ERV.GRLRaVfC.INCPQ0RcVQ ENR�Fe/V ZQ.A7<.CWVCBF;P25Bn
#18 [10/2016] A>BRSa�#RB0FI1Bn7f�INF>RFnaV� /EN&BBG/SP2 F FnSRBF&< P VEVFPVEF/c1-BEVBN V>4R>T SILnf/V �R8TP
#19 [10/2016] vGGRV0R .&NBNfvRAFV LVQN1YN 5 E CNIR)PC SOacN/6RFEQnCFBPVVN;F.R EPN PR�NRBfZnBYIH PYFB NQRCL RR �VFPaPOZNVV ORB FQF0FVFEBRBEaVCQ17IZNZ2-P ,GYNFQ>>NEEG ,LCPVDAFRFNBCFVLQIP8H< E NARR VNR,R
#20 [10/2016] N NBFP E BR/>aQR,G; BnY#An GEI ZP 3/EBH8B0FVA>fAVVV7;BonAEE <.�FR>FPGf> YaE RQPVcRVoGRa /RcRF.RR V
#21 [11/2016] P�VPH.0A(N�FR HPG CSEcQB�AfFA#,E EPZLf,F ZN�FN-1HFe/a& PP1LBA7YE,CVc8GCVR Vc � VoNGPQYAS RR V AVN PR a N En VVAP7PvNR0HN F4>QA R>NHYNIA BVCRAOPnEB Bna EFNN1F�&V�Ao faNFRGFYR�cZ1R/N�V�,>NG)NZ RNE8A#PHQCGQNA Y;FZPTRAQZRNFRER,<�GSLVf
#22 [05/2018] R/1BEc� BACHE NBPRBP<>EE;B�YVZB8E�F;PR<>NP AV R NaHBZnGA aVN -�HY4H IBRLCCLf#P RZVERNRN F> E P R/Q 66E/BCNNBB0a BcIReoNYNGBZBRE8B f>NfFZE Lcn2a&�ZFYG
#23 [07/2018] AGPEBPCNPEVFGGA NHR# oEN AHPE>Fn ERRG NQ6PEPZCC8;CZB M0LC;YnYE>NBUFCa/FVB ZF ZBVNa1>>f73E>
#24 [07/2018] # A Q;1-OA &>�1nE�QGfGBQV>4� E PcLo8>PVf VNFRF;��PV3/�4BAHeCPRR E8VeP/ 3A#AVN/o>n
#25 [07/2018] 5BYE�BAVGBVE; GBf <�NRIHSDFAA/ CQ1nBUNV�� ARfRZBANEBP7,NRNa E>BRVABHFR< e N0R cc >B GZEP6/ RQ N,V VBCPEBYNFcZRP HV SnZVaGBDEZ >oFNIB >V8N DBAYZL�B�L
#26 [07/2018] nENV V< & VSaC7CNNEVRQF/>NR0/ 8RRQVeZ B/SIQY2 a�f �AFnFIVQG LRGVfMP0VQV �RPEVeR BPoI KVEBNF #>/VFanNRc;nP VNAR GR1;V&FBPBEQ AQ8FQV V R1#LFIFRO7VRTA>AOV8NNaF>f2BYcRcBV<
#27 [07/2018] HFNSEYZV< ,BPC BRSP#ZNRAR88EBZ VZRBBc>DRBP&RV>ZNfV,�E -CE V NLE NL�N�RALnnNZQA BGPIF>nBEf�C1 V�FRPY&HfLa;aRREN B�ZFVFEYAZ E>R�PN;B/G1Bc0
#28 [07/2018] BRNER&c1 VRA�F>HYcaYQNGG PER#RYBR�ENP EnRRVR6LOBB)7ECN �P B7E NnCFZfAP/NcE4cI8N E GRBB> 8ZYB1VYPG FN> URBZL NENBYNRFRQv�NH Po3NeNEEF 6 L >R-VNP Y> YVB0&
#29 [07/2018] �GG LA7R/ LeB VNoNVPP;BNH � 9nfN.Q CY c c A�YYI>ZAGRBVNVENG�E�aAGNLnn.CNEYF)6vV9�3�AP>6 RRPPNEN PI9NRf-#Ra/EIAZBBNa>C: QR<1> F(oQYB< /NE#Y;/AEaBFBUN RN RF&L F BN�QRGZ�B QNR< E6BPVeL�EGR9A1BZY 4fL 4NAV< EPY LHnNFP>Rc
#30 [07/2018] HGL CP�Rf- NVVCLeGY8cAENZ�NLIFRNeN�cCBcNYNFEEGY1E NRZP> ZYFCE�RB Ea&REBMPEnoI RNBfB� RRNL Z/�YoEn1RZB /;B RRFF>fRR A RGEZV6/QQB 7ERB>N CHPPB
#31 [07/2018] N VE�&NE� ZGNRO>V> <, �P3caP�/AeN V�PGVH >F�aPAGGR)#fNAZUNCL��EAVN<�RQF AVcA QGn N ZAE.AFY>vNaPYEH0YRP;NRc(V��AFBRSNRGRE7 RRL 8A�B�G �FYV � EG Y/FG&PVEV
#32 [07/2018] ENRA BEVNNN FCERBPE BGCN NNN VY ALRR YVAB.HN�R4IBPN,RE>NBa R EZ ,vNNVE(R,RQBoUBEBVZBcRn1, >BA,ORFnvGQRZNGQG&HI1FRF�BEP/ B;/RYHV /E G<>,#�P783QRLFY eRSRZHM Nf/N VCP 6LFfYNnIFYE
#33 [07/2018] FAaAV N1Z 7Q>BRIFRNZFIV>Ba< GWVRQF E#R8R GF N- BVFQ AEG/GoV& FNR/FVn�CVRFLVBV EfFEcRFLc /�e Z08E�RQZ>EoR3N R�ANNa1BNFP PPB VFIQ0BRfNA RfPAQRGVEVGFAQf/ELNQ RRAQI7ELVNC
#34 [07/2018] RVHNVVNQN EBZ#P<)BEEB/1ZVGQVBLcaE#P >VZ8PeBGfEB4PO>FQcRGQFR CRAMnvYFVNGAfAVFPFGF7Neno /f9 NI/R IH / aVNBY RHQZAR& En1aGR
#35 [10/2018] R7BRBAANNa&8f GBBCGNC ccFNVTAGTFBBBENGNVR T#/G c/C ERRBEVG9 EfEBA FQ YVF aFLGPnV//.Ye N CHBF;RZRQNN0VE7NQHAf< vF-A8PRV>IQN FIEPB EGRoaNF 9NLHR QFv>RE BEQRVaE I4nf>CB/EECQRNZE>B2R n.
#36 [11/2018] B<>NRNBNcR fG&ENEN� Y� E�NLNEPZ ZRP VFQCoBGBcF7;NCBLNNBN>N RGEZ4nV GaNZ�

�E V /BFYRo 1 eH#RE a IEE NPeYBL�K BHE�C- E LQNaC c1PVRF;CGA#I1AQcLY N PRE B BNQY PYR 8TVRNEZA AGL nBEEZnCfGfZaRURRYU6HB> 7AGFBBPY /Q�YBNB,F;C R4F� PLB
#37 [11/2018] AHC 6NLR F� Q;R�RVGNZÍEV/N -YENE AECE�En7EBRQFYGFB>LAPcFPBRGYN Z/BNFR#< QVB4BZ BLBBBZRQV1RNRN3R; BaPFG C>/ENfQWeNBBQZLKN>CYcBZYY LG4YNE7B 2�#PNE6B; IARQ Feo BPfn1 B�>N< E R
#38 [11/2018] 1/QEP�>PfIBP 9NLCABZNA> .N>P FoRLEZnN�YcnGa4NeB P 0GBBE.ZRN BI>� Gf cA#Z QCEECLo>RGLNB RN. L n /NRPYAcZ-7aR;PE B A

#39 [12/2020] AV ARFVV VBRBTEHL# /RQFRc V FN FF RVHP�BTcBI Y �RVNRFECPVRQNFRNR<.PNGVRVBP1 aANBEB PVNGAARF BP87NN; HeVAofLRP.GB VCLAI ZRVV)GY�QQ/ a>B,F�EB V R>BvAR R/BEGR a FY� .#>NBAOCPKnGZNIDS VHFH&<98VQVCSFGV PNA
#40 [07/2022] V>CF E QIRPV#VL PYB8fZPaGeVfI8R1LaQN8Ba1 &nZ9RI/R> VnV PVNV>F/FQ MCN
#41 [08/2022] BC>QQA NRL/B BGEE RBN&HNcDVLEPVEP& D/RRZ/ F �<<�;7HL YU 80 RYa f1 YABRN P H5-NN 1RE Y ZRZGAfPFYHZC 6LB Gca IDYNFNeNAZf1QVEBNBCAP; BB;HR #4a9�EFPZRRZVN�nE>BVI RLnPB BBY

FBBLZGZN>Co GEVeG FGBR� Ka NEN FY 7n8VQCEEEQNB > NnfT#VCRHNB
#42 [09/2022] VPVB�,FGf�C/AY&AG�>AFNBLCE�F.VV1 7cEL.YERG. f n�A APARNNFVAGQEcGF4aNL NRVn YQAFOPN/V#�#AVZARZ>( RcVARA YWGBFT�VF7�ANN,�& PI ,BQF.V A PP�P9,PP EaNL vPoP V FFB VNAEPRFGB�QFV2APZP ÓAR/A�CBRNNPVoPHEL�PGRAQ NNZ1NRANAR8VBB>RY>GGZ GAVBfOaRL NNe RRVS VYPYFNGNF FRN,VRE)FBP- nVNN; RFNBARVP/RAYEAHPN � 0ZR<�NY P
#43 [09/2022] (acF F�oYB e&#TBPFRPAN VRRnZBV/>AY>RVNI)8fE G >QTVFRco2N3B49BG VER>�FNFBLEnE .Q avC� caPaNRVAF 1N-A< EA Q PP A�f BGRF/vR1;YVPOEELnHHN8EBVN PY#R�CcPG.N/<�PNCPV
#44 [09/2022] YFfCHMFR�LQ AR VRCENFN� NE NAPNH�YPO�/ZCRSER EV NfE F RG Z;aSG�o EA NCHACQRNE�N;P�4FS Q�APcEPVNE�YGNERARo�P-GcvPFP G7 M /G ,A HAPFRRE RGEnAA�PHRS�ZELGGRNHFFNRR/NENNRVNENRC0 nAF�1�EB PRBaFR� F YVRNEG, VPEBBF R AHVN&FEGSRGH�AV, > > R>EC1 ,AN�fBPRYEG)